Oxiracetam – What it is
Oxiracetam is a nootropic drug of the racetam family and a very mild stimulant. Several studies suggest that the substance is safe even when high doses are consumed for a long period of time. However, the mechanism of action of the racetam drug family is still a matter of research. Oxiracetam is not approved by Food and Drug Administration for any medical use in the United States. There has been effort put into investigating the possible use of oxiracetam as a medication to attenuate the symptoms of dementia. However, no convincing results were obtained from studies where patients suffering from Alzheimer’s dementia or organic solvent abuse were given 800 mg of the drug orally twice daily.
Oxiracetam – What it Means
The proven effects of the drug are limited to beneficial effects that lead to higher scores in tests for logical performance, attention, concentration, memory and spatial orientation. These tests were performed on patients with mild to moderate dementia and ADHD, and the doses were 800–2400 mg orally twice a day for one to six months. Improvement has also been seen in patients with exogenic post-concussion syndrome, organic brain syndromes, and other dementias. According to V. Gallai et al, oxiracetam is more effective than piracetam for this purpose.
Oxiracetam – What it “Does”
Research shows oxiracetam improves hippocampally-mediated learning performance by increasing membrane-bound protein kinase C (PKC). When compared to control mice, oxiracetam-treated DBA mice demonstrated a significant increase in spatial learning performance as determined by the Morris water navigation task. This increase in performance was correlated to an increase in membrane-bound PKC.
Oxiracetam is water-soluble and more potent than its predecessor. It has been shown to boost long-term memory and recall and improves attention, concentration, focus, and motivation. Unlike Aniracetam, Oxiracetam does not attenuate emotional well-being. It doesn’t make you “feel” better, but it does enable you to function at levels up to 30% higher (as shown on test scores) than a placebo. Oxiracetam also improves spatial and contextual learning, and logical and critical thinking as well as analytical reasoning.
Like most other racetams, oxiracetam influences the Acetylcholine system of the brain. Research has shown that oxiracetam may be helpful in the treatment and protection of the brain from the damages of alcohol and drug abuse. It shows a strong possibility of possessing neuroprotective and antioxidant properties and is sometimes used to treat cognitive decline brought about by age. Oxiracetam is generally considered safe with no known side-effects. Excessive consumption may lead to headaches brought about by choline depletion but this is easily solved by taking a choline supplement. All Gnutropic nootropics are buffered with a source of choline to help eliminate this possibility.
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